Furthermore, triple immunostaining experiments indicated that the expression of pericyte-p-MLC2 was decreased in tumors arising from the mice that were co-injected with A549 and HK2-depleted TPC as compared to A549 co-injected with scramble transfected TPC, whilst its expression was enhanced in the tumor-derived from co-injection of A549 cells and ROCK2 overexpressing HK2-depleted TPC. This evidence concerns the gene HK2 and neoplasm.