The most common (≥20%) TRAE included 33 (82.5%) leukopenia, 28 (70.0%) neutropenia, 27 (67.5%) anemia, 21 (52.5%) elevated AST, 20 (50.0%) elevated ALT, 19 (47.5%) nausea, 19 (47.5%) thrombocytopenia, 15 (37.5%) decreased appetite, 11 (27.5%) constipation, and 10 (25.0%) asthenia. This evidence concerns the gene GPT and anemia.