CARD19 and infection: To test the possible contribution of CARD19 to cell death during pyroptosis, we compared the kinetics of cell death in primary bone marrow derived macrophages (BMDMs) from B6 mice and mice with a targeted deletion in Card19 generated by Lexicon Genetics (designated Card19lxcn), in response to infection by Salmonella enterica serovar Typhimurium (S. Tm) or LPS+ATP treatment.