ADIPOQ and Abdominal obesity: A small sample-sized, population-based cohort study reported that SUA levels are inversely associated with adiponectin, a fat-derived hormone protective against cardiometabolic disease.18 Based on this previous finding and the role of central obesity as an independent risk factor for albuminuria,39 it remains unclear why WHR and BMI did not mediate the association between SUA levels and ACR.