Interestingly, we identified not only upregulation of COL4A1, COL4A2, COL5A1, COL12A1 but also an increased expression of laminin subunit alpha 5 (LAMA5) and gamma-1 (LAMC1) in 10NQ cells, suggesting the reorganization of self-ECM components of cancer cells in response to altered integrin expression and N-glycosylation. The gene discussed is COL4A1; the disease is cancer.