Most of these studies selected gene expression profiles in glaucoma and trabecular mutilation, and in each of these data-related analyzes, different genes, such as LCN2, MAOA, HBB, PAX6, FN1, and CREB1 [56] and COL4A4, COL3A1, COL1A2, ITGB5, COL5A2, and COL5A1 [57], and collagen, actin, and cell-matrix interactions were examined. Here, CREB1 is linked to glaucoma.