As shown in Figure 8B, AKR1B1 (p = 0.000988), AR (p = 0.0102), ITGB3 (p = 0.0389), MMP2 (p = 0.0465), PTGER3 (p = 0.0449), and PTGFR (p = 0.0439) with the p values were all less than 0.05, suggesting that these genes may be the key targets affecting the survival of GC patients. This evidence concerns the gene AKR1B1 and gastric cancer.