AKR1B1 and gastric cancer: The overlapping targets (AKR1B1, TLR4, ESR1, PRKCQ, PIK3CD, CTSK, MMP2, ADRB2, PDE1C, ITGB3, PDE10A, PTGFR, AR and PTGER3) were considered as the key genes for the CKI treatment of GC.