SPP1 and metastatic malignant neoplasm in the lymph nodes: The qRT-PCR assay was performed on 25 cases of tumor tissues (12 cases of lymph node metastasis, 13 cases of non-metastasis), we confirmed the significantly increased expression of SPP1 (Figure 8A, p < 0.05) and the significantly decreased expression of lncRNA (AC037441) (Figure 8B, p < 0.05) in the lymph node metastasis group.