The HIV infection stages of these patients according to the WHO classification are as follows: 1 patient had no adverse event (CD4 > 500), 2 patients were mild (350 < CD4 < 499), 7 patients were advanced (200 < CD4 < 349), and 10 patients were severe (CD4 < 200) (Table 1). The gene discussed is CD4; the disease is HIV infectious disease.