CD8A and COVID-19: All HIV patients showed typical features of compromised immunity: the mean CD4 T-cell count (226 cells/μl) and the mean CD4/CD8 ratio (0.5) were reduced below the mean limits of the reported patients with either severe (CD4 = 263 cells/μl, CD4/CD8 = 1.5) or moderate (CD4 = 451 cells/μl, CD4/CD8 = 1.7) COVID-19 (Qin et al., 2020), and these were reduced more profoundly in AIDS than in non-HIV-infected COVID-19 cases (CD4 = 347 vs. 104 cells/μl, p < 0.001; CD4/CD8 = 0.7 vs. 0.2 cells/μl, p < 0.001, respectively) (Figures 2A–D).