Given that G‐MDSC can mediate immune suppression through both antigen‐specific T‐cell suppression, such as ROS production, and non‐specific mechanisms, such as the production of arginase 1, interleukin‐10, and cyclooxygenase‐2 (Bronte et al., 2016; Zhou et al., 2018), we believe that IF can also increase the antitumor effects of T cells in the cancer host. The gene discussed is ARG1; the disease is cancer.