circAMOTL1L, derived from the circularization of the exon-2 and exon-3 of the Amotl1 gene, was reported to exhibit a tumor suppressor characteristic in prostate cancer by modulating the miR-193a-5p/Pcdha axis to suppress the migration and invasion of PCa cells [25]. This evidence concerns the gene AMOTL1 and Familial prostate cancer.