AGT and triple-A syndrome: Four weeks after Ang II infusion, macroscopic examination of the aortas demonstrated that 45% of mice (9 of 20) showed dissecting AAA formation and 35% of the mice (7 of 20) experienced rupture events when treated with AAV-GFP, whereas AAV-LH1 treatment exhibited strong inhibition of the incidence of the formation of dissecting AAA (2 of 20) and rupture (1 of 20) (Figure 5C-D).