ELANE and Sepsis: The NETs-extruded products, including citrullinated histones (Cit-H3), granular enzymes neutrophil elastase (NE) and extracellular DNA, function as the damage‐associated molecular pattern molecules (DAMPs) to initiate immunosuppression 7, which is found to be associated with the extremely rapid course of inflammatory storm and tissue injury elicited by sepsis 8.