AKT1 and cancer: The lncRNA small nucleolar RNA host gene 1 (Snhg1; Gene Bank: 23642 (human), 83673 (mouse)), which was originally identified by its oncogenic activity 18, was shown to promote cancer cell proliferation by activating the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) signaling pathway 19, 20.