NLRP3 and experimental autoimmune encephalomyelitis: Some small-molecule chemicals, such as MCC950 65 and Bay 11-7082 66, suppressed assembly and activation of the NLRP3 inflammasome and reduced the severity of NLRP3 inflammasome-driven disorders, such as cryopyrin-associated autoinflammatory syndrome or experimental autoimmune encephalomyelitis in mice.