In addition, there are some risk factors for CP-induced nephrotoxicity including sex, history of renal dysfunction, drug dose, and the frequency of drug administration, older age, female gender, and hypoalbuminemia [1, 5, 6], while diabetes and organic cation transporter 2 (OCT2) polymorphisms are considered as decreased risks factors for CP-induced nephrotoxicity [1]. Here, SLC22A2 is linked to Abnormal renal physiology.