RAD51 loading and strand invasion are mediated by many factors including BRCA1, BRCA2, five RAD51 paralogs (RAD51B/C/D, XRCC2/3), members of the Fanconi’s anemia (FANC) protein family, RAD54/B, and RAD51AP1 and its paralog NUCKS1 (Pires et al., 2017; Wright et al., 2018; Niraj et al., 2019; Maranon et al., 2020). Here, RAD51 is linked to anemia.