RENBP and glioblastoma: The ECM-receptor interaction, focal adhesion, AGE-RAGE signaling pathway in diabetic complications, and proteoglycans in cancer were also associated with upregulated genes in GBM (Figure 2B and Supplementary Table S3), whereas the neuroactive ligand-receptor interaction was associated with GBM downregulated genes (Figure 2B and Supplementary Table S3).