NEFL and Spinocerebellar ataxia type 3: Plasma NfL levels were about 4-fold higher in patients with SCA3 than in healthy controls (34.8 vs. 8.6 pg/ml) and correlate with disease severity, disease progression and CAG repeat length of ataxin 3 gene mutation (Li et al., 2019; Peng et al., 2020; Wilke et al., 2020).