AIF1 and Alzheimer disease: The double staining results revealed that the number of Iba1+iNOS+ in AD mice (average 39.0 of CA1 and 26.8 of DG) increased, compared with Control (average 19.8 of CA1 and 13.2 of DG) and NS (average 19.2 of CA1 and 13.0 of DG) (p < 0.05) (Figures 3A1–3,5, B1–3,5).