On the other side, immunotherapy with checkpoint inhibitors is becoming the standard of care for many cancer types, such as skin [5], lung [6], renal [7], or bladder cancer [8], and immunotherapy against specific antigens is standardized as a treatment for early or metastatic HER-2 positive breast cancer [9, 10], metastatic colorectal [11], gastric [12], ovarian [13], or cervical [14] cancer. This evidence concerns the gene ERBB2 and cancer.