NF1 and metastatic neoplasm: Although a significant difference in survival was not found based on presence of an NF1 diagnosis, patients with NF1 trended toward a poorer outcome, particularly males: one was still alive at the last follow-up at 314.8 months after metastasis, but three (including one with metastatic disease) had survival under five years (52.43 months after metastasis, 13.74 months after diagnosis, and 17.23 months after diagnosis, respectively).