CD63 and Sepsis: The level of exosomal CD63 was higher among patients with septic shock (90 μg/mL, IQR 49–140 μg/mL) compared with healthy controls (6.6 μg/mL, IQR 4.8–11 μg/mL) and sepsis patients without shock (42 μg/mL, IQR 22–90 μg/mL, p < 0.001; Fig. 1).