In fact, long-term consumption of a MedDiet rich in extra virgin olive oil was linked to a reduction in the plasma/serum concentration of pro-inflammatory markers such as interleukin-6, a C-reactive protein, adhesion molecules and in the chemokines in the PREDIMED (Prevención con Dieta Mediterránea) Study41,42, where the MedDiet reduced the relative risk of major cardiovascular events in patients without ASCVD. The gene discussed is IL6; the disease is atherosclerosis.