As was previously described, WT PopP2 delivered by Pf0-1 triggered a cell death response already at 24 h post-infection (hpi) in the resistant Ws-2 accession carrying the RPS4 and RRS1-R genes but not in rrs1-1 null mutant (Fig. 5a, photographs were taken at 3 days post-infiltration). The gene discussed is RRS1; the disease is infection.