Similarly, case 21DG0001 with a homozygous truncating variant in TNNT3 (NM_006757:c.723-2A>G) presented with severe non-immune hydrops fetalis and neonatal death (Additional file 2: Fig. S5), which have not been reported to date in TNNT3-related myopathy. This evidence concerns the gene TNNT3 and myopathy.