To test whether increasing levels of 2-AG would ameliorate the inter-trial phase coherence (ITPC) deficit to auditory chirp stimuli seen in previous studies with adult Fmr1 KO mice [28], and humans with FXS [23], MEA responses to repeated chirp stimuli (300 trials) were recorded prior to treatment (PRE), 4 h and 1 day post-treatment. Here, FMR1 is linked to fragile X syndrome.