We also evaluated the clinical and laboratory characteristics of the MTHFR (rs18011131 and rs1801133) and VEGF (rs2010963) tumors that showed significant differences in the BCLC classifications shown in Table 1, namely mean serum AFP level, Child-Pugh score, mean tumor size, and the relationship to the best genetic model (Table 5). The gene discussed is MTHFR; the disease is neoplasm.