Immunosuppression was reported in 22 patients and was related to ongoing therapy with anti-cancer chemotherapy (n = 1), ustekinumab (n = 1), methotrexate (N = 5), TNFα antagonists (n = 5), prolonged corticosteroids with or without other immunosuppressive drugs (azathioprine (n = 1), mycophenolate mofetil (n = 1) or corticosteroids alone (n = 4)), or HIV infection (n = 3), or Good syndrome (n = 1). This evidence concerns the gene TNF and cancer.