Comparisons were made among proliferation, migration, and apoptosis induced by Apo2L/TRAIL in Jurkat T cells and LS174T-Tn+ cells isolated from CRC cell line LS174T that were untransfected and transfected with WtCosmc Tn+ cells harboring mutant Cosmc. This evidence concerns the gene TNFSF10 and colorectal carcinoma.