There was positive correlation between the magnitudes of fold change of differentially expressed genes in glioma patient plasma samples and the mean FPKM in TCGA glioma-derived RNA samples: BCL2, BCL2L1, CCR2, CXCL5, CXCL9, CXCR3, GBP1, GZMB, HIF1A, HLA-A, HLA-C, IL23A, IRF1, MICB, MIF, MYD88, TGFB1, TLR2, and TP53; Spearman r = 0.4614, n = 19, p = 0.047, see Fig. 5a. Here, HIF1A is linked to central nervous system cancer.