CCL2 and cancer: Nonetheless, it is said that there is a communication between the peripheral cytokines and central cytokines because many studies have shown an elevation in cytokine levels such as TNF-α (tumor necrosis factor-α) and IL-6, IL-8, IL-10, (interleukins), and MCP-1 (monocyte chemoattractant protein-1) in cancer patients and were prominent in people with dyscognition.