Moreover, according to AACR GENIE, in human the NRAS p.Gly12Asp was detected in acute myeloid leukaemia, colon adenocarcinoma, colorectal adenocarcinoma, rectal adenocarcinoma, acute myeloid leukaemia with myelodysplasia-related changes and in melanoma patients [22]. The gene discussed is NRAS; the disease is colon adenocarcinoma.