qRT-PCR and western blot assay revealed that knockdown of NNT-AS1 decreased the mRNA and protein levels of YBX-1, while co-transfection of siNNT-AS1 and miR-137 inhibitors rescued the inhibition effect of siNNT-AS1 in ccRCC cells (figure 6f). The gene discussed is YBX1; the disease is nonpapillary renal cell carcinoma.