Specifically, the expression levels of NLRP3, ASC and Gasdermin D in AP rat tissues (Figure 3A), and the pro‐inflammatory cytokines (IL‐6, IL‐13, TNF‐α, IL‐1β and IL‐18) in AP rat serum (Figure 3B‐F) were much higher than that of normal rats, indicating that cell pyroptosis and inflammation occurred during AP pathogenesis. Here, GSDMD is linked to alkaline phosphatase measurement.