AGT and alkaline phosphatase measurement: In this study, we firstly screened out a novel tsRNA tRF3‐Thr‐AGT that was aberrantly downregulated in AP, and upregulation of tRF3‐Thr‐AGT rescued cell viability, suppressed cell inflammation and pyroptosis to attenuate AP, which were partially supported by the previous work,49 indicating that tRF3‐Thr‐AGT was a potential diagnostic and therapeutic agent for AP treatment in clinic.