In the transethnic meta-analysis, the phenotypes with the strongest association with variants near ABO locus (rs495828 and rs505922) was “hypercoagulable state” (ORcritical_PheWAS = 1.48 [1.42 – 1.54], Pcritical_PheWAS = 1.84 × 10−40; ORhospitalized_PheWAS = 1.51 [1.46 – 1.56], Phospitalized_PheWAS = 2.11 × 10−55, Fig 2). Here, ABO is linked to thrombophilia.