We retrospectively compared the averaged NRAS read counts from 21 other EGFR mutant patients who were treated at the University of Colorado Cancer Center between 2018 and 2020 and had the same clinical NGS assay data and found that none of the other patients had detectable NRAS amplification, with average read counts in the same range as normal controls (Supplementary Fig. 3, a). This evidence concerns the gene EGFR and cancer.