Several biomarkers, such as IL-6, IL-8, IL-15, IL-10, IL-13, IL-17, TNF-α, IFN-γ, and granulysin (GYLN), are increased in the skin lesions, peripheral blood mononuclear cells, and plasma of patients with SJS/TEN20–26. Here, TNF is linked to Schwartz-Jampel syndrome.