PacBio sequencing of tumor detected 128 breakpoints, of which HBV was integrated into repeat region in 21 reads, into intergenic nearest CCNE1 (Fig. 2d) in 63 reads, into TERT promoter-TSS in one read (Fig. 2c), into SYT14 intron 3 in 21 reads, into SERTAD4 intron 6 in 18 reads, into MIR12125 in three reads, and into MIR4457 in one read. The gene discussed is SYT14; the disease is neoplasm.