Immunofluorescence staining showed that vezatin (green) expressed in the hippocampal CA1 region in mice colocalized with the neuronal marker microtubule-associated protein 2 (MAP2) (red) (Fig. 1c); the mean fluorescence intensity (MFI) of vezatin was higher in the epilepsy group than in the control group (especially in the stratum radiatum), indicating increased expression of vezatin in the epilepsy model (Fig. 1d). Here, VEZT is linked to epilepsy.