CD8A and interstitial lung disease: Further analysis of different types of extraglandular manifestations in pSS patients showed that the percentage of CD8+GranzB+CTLs were significantly elevated in the pSS patients with ILD, purpura, PAH, and autoimmune liver dysfunction (p < 0.05) (showed in Sup Fig. 2) and correlated with IgG, ESR and NK cell% (p < 0.05) (showed in Sup Table 1&2).