The study reported by Ogunymi et al. was characterized by significantly different gestational ages at enrollment (metformin vs. insulin, 28.1 ± 7.6 weeks vs. 24.6 ± 8 weeks), and therefore this study was not included in the meta-analysis to avoid introducing bias, despite the fact that they reported similar results to those of the present study with respect to the effects of insulin and glyburide on 2HPG control and the prevalence of neonatal hypoglycemia [51]. This evidence concerns the gene INS and Neonatal hypoglycemia.