The expression levels of CD8A (encoding CD8, marker of CD8+ T cells, Fig. 3E), CD4 (encoding CD4, marker of CD4+ T cells, Fig. 3F), and CD3D (encoding CD3, marker of T cells, Fig. 3G) were also significantly high in the low-risk groups, indicating higher abundance of the tumor suppressor T-cell subpopulation. Here, CD4 is linked to neoplasm.