The viral immunological response produces cytokine storm in severe infections which are characterized by an apparent increase in cytokines (IL-2, 7, and 10), IFN-γ-induced protein-10 (IP10), granulocyte colony-stimulating factor (GSCF), monocyte chemoattractant protein-1(MCP1), and tumor necrosis factor-α (TNF-α). The gene discussed is TNF; the disease is infection.