Elemene reduced metastatic tumor nodules in a mouse metastasis model constructed with SGC7901/ADR cells and reduced the expression of miR-1323, Cbl-b, and E-cadherin in the lungs of nude mice, whereas vimentin, MMP-2, and MMP-9 were significantly downregulated [21,57]. The gene discussed is MMP2; the disease is neoplasm.