CDK8 and Carcinoma, Lewis Lung: C57BL/6 mice were used to detect the CDK8 gene expression in the blood of mice in each group, and a Lewis lung carcinoma mouse model was used to observe the tumor growth and detect the Cdk8 gene expression in the tumor tissues, which were all divided into four groups including a model group, elemene group, doxorubicin group, and combination group for treatment.