Colon carcinoma HT-29 cells in the permeation solution through PLGA-3/SK and PLGA-10/SK filters secreted a similar amount of CEA as the cells cultivated on TCP dishes (control), whereas the cells in the recovered solution and the migrated cells via NM-11 and PLGA/SK filters generated higher CEA production than the cells cultivated on TCS plates (control) (p < 0.05). Here, CEACAM5 is linked to colon carcinoma.