In particular, the cells migrated via PLGA-10/SK filters secreted the highest amounts of CEA compared with other cells in the permeation solution and recovered solution via any PLGA/SK filters, as well as the migrated cells from PLGA-5/SK and PLGA-3/SK filters and extensively higher production than the colon carcinoma HT-29 cells incubated on TCP plates (p < 0.05). Here, CEACAM5 is linked to colon carcinoma.