PNPLA3 and cirrhosis of liver: In a recessive model, the presence of the PNPLA3 GG genotype was markedly associated with a greater likelihood for liver cirrhosis development (OR 95%CI = 4.03 (1.93–8.41), p = 8.4 × 10−5), and significant associations were also found in dominant, codominant and log additive models (Table 2).