Medications for diabetes control were different among groups; metformin (89.2–94.5%), sulfonylureas (68.1–68.8%), dipeptidyl peptidase-4 inhibitors (66.7–71.4%), and sodium-glucose cotransporter-2 inhibitors (17.2–20.9%) were used by a higher proportion of subjects in the normal and possible groups, whereas the proportion of subjects in the confirmed group who used insulin (65.6%) was higher than that in other groups (Table 2). This evidence concerns the gene INS and diabetes mellitus.