Polymorphisms in the sequences of some genes (CFTR, CTRC, PRSS1, and PRSS2) that have been associated with the risk of pancreatitis in general have been described in the literature [38], and in 2016, Liu et al. published a study reporting the finding of a nonsense variant of the CPA2 gene encoding carboxypeptidase A2 associated with an increased risk of AAP [39]. This evidence concerns the gene CTRC and pancreatitis.