NLRP3 and type 2 diabetes mellitus: Aberrant activation of the NLRP3 inflammasome leads to excessive inflammatory response which is involved in the occurrence and development of a variety of human diseases, such as gout [2,3], osteoarthritis [4], tumor [5,6], type 2 diabetes dillutus (T2DM) [7,8] and neurodegenerative diseases [9,10].